2023 Spring Allotrope™ Connect
Allotrope Connect (Spring 2023)
Bringing together Allotrope members and the broader scientific community to discuss how we are delivering faster insights from new and existing data within organizations by improving standardization of data and its interpretation across laboratory and manufacturing operations.
With over 50 data models, and growing, Allotrope is leading the way in data standardization thereby allowing quicker access to insights within data.
Registration Site is Closed
If you would like to attend remotely, please register by clicking here.
Please complete the registration to receive the remote connection information.
Day 1 Recordings
Day 1 recordings are available on the Allotrope YouTube Channel by clicking here
Agenda (Detailed agenda: here)
Day 1 (April 25)
-
Public Session: "Allotrope in Action" - Presentations from Allotrope Foundation and Allotrope Partner Network Members
-
9:30am - Welcome and short introduction to Allotrope Foundation and Technology (Corey Bakalarski, Allotrope Foundation). View a PDF version: here
-
10:00am - How open-source projects have been made possible by CC ASM (Maxime Visconte, IFPEN). View a PDF version: here
-
Allotrope Simple Model has been released under the open Creative Commons license. IFPEN demonstrates how this allows the plan to build an open-source library for the ASM written in Java and release it to the public to become a reality. The presentation will feature an overview of the components already publicly available, and a roadmap for the next month.
-
-
10:25am - Automatic Sample preparation (Diego Olivares Garcia, Novo Nordisk)
-
Workcell to automate sample preparation for chromatography analysis.
-
-
11:00am - LC-UV Methods and Results Interoperability using ADF (Azzedine Dabo, GSK). View a PDF version: here
-
Digitizing Analytical Methods - The methods Hub Project: Currently analytical methods used in the pharmaceutical industry face the twin challenges of interoperability and reproducibility due to the methods being stored and managed in paper form. They also are frequently stored in proprietary software platforms. Improving automation and interoperability of analytical methods may improve quality, enhance efficiency, and reduce cost. Such benefits are expected by enabling digital b2b method transfer (e.g. from CRO to Pharma), reducing manual entry and cost associated with human transcription errors, faster reproducibility, enhancing data use and re-use with thorough contextual meta-data, and improving out of spec (OOS) analysis capability. Looking forward, this infrastructure may help leverage data standard for machine-learning. In essence, easier compliance fosters more science.
-
-
11:30am - Automation: the new frontier for Allotrope? (Frederick Francois Chesneau, BASF). View a PDF version: here
-
We will walk through a proof-of-concept implementation of Allotrope Simple Models to provide standardized data for synthesis workloads at BASF. In addition, we will go through the motivation and general approach we are currently following with a live demo of the current demonstrator. We will touch on IoT and sensor topics as well.
-
-
1:00pm - Accumulus FHIR Overview for the CMC data (Sheetal Gaiki, Johnson & Johnson, and Rita Algorri, Amgen). View a PDF version: here
-
FHIR’s capability for enabling exchange of data across a variety of formats and systems has many use cases including for CMC regulatory submissions. For this paradigm shift to occur, industry sponsors must match the investments in structured and standardized data put forth by health authorities. One such initiative includes HL7’s BR&R DX-PQ initiative spawned from the sponsor companies supporting the non-profit organization Accumulus Synergy, which is developing a FHIR Implementation Guide for Quality Data.
-
-
1:30pm - Advances in Data Utility through Application of Process & Reading Ontologies in BIOVIA ONE Lab (Kirsten Gesenberg, Biovia). View a PDF version: here
-
In the past, when capturing and working with experimental data produced by instruments, the limited application of ontologies has resulted in complex, poorly defined data structures that inhibit the constructive use of the data produced. Early efforts at improvement required complex, ad hoc application of parameter naming and tagging. At BIOVIA, the recent application of more carefully defined result and process ontologies creates a much cleaner, more well-defined approach to structured data, providing a more accessible and reusable data format.
-
-
2:00pm - From Chaos to Clarity: ZONTAL's Digital Solutions for Biotech Wizards! (Dennis Della Corte, Zontal). View a PDF version: here
-
Welcome to our talk about the ZONTAL Application Hub, the innovative digital solution that is designed to streamline data management and analysis for biotech companies. Our platform leverages the Allotrope Data Format, Ontology Model, and the Simple Model, providing new applications that are bundled into tailored solutions for biotech companies. In this presentation, we will highlight some key applications of ZONTAL that can help to enhance the daily activities of biology and chemistry laboratories. Our user stories will showcase how our platform can offer you a competitive edge and enhance your productivity. One of our major focuses will be on the Flow Cytometry application, which is an essential tool for analyzing cells and their properties. Flow Cytometry generates complex data, which can be challenging to manage. Our platform provides a user-friendly interface for data management and analysis, which can help researchers streamline their workflows and make better use of their data. Overall, our presentation will provide an overview of the ZONTAL platform and its applications, highlighting how our innovative solution can help to enhance your laboratory's efficiency and productivity.
-
-
3:00pm - Accelerating Bio-Tech innovation through instrument data standards (Nick Floeck, Benchling). View a PDF version: here
-
Join us in this session to learn how instrument data standards can enhance scientific workflows & drive more efficient & automated research and development processes. Explore how Benchling can help the Allotrope community to operationalize Allotrope standards as part of a modern, end to end, smart R&D workflow that helps accelerate Bio-Tech innovation.
-
-
3:30pm - If your strategy depends on data, you need a strategic roadmap to deliver data worthy of the aspirations (Dana Vanderwall, DLC)
-
The aspirations to be more data driven, or leverage predictive capabilities more heavily, are inescapably tied to the quality and availability of that organization's data. To go beyond targeted PoCs or prototypes and enable data across the enterprise to fuel those aspirations requires a strategic view of the full breadth of data across R&D and a roadmap for transformation of the lab data architecture and systems. This presentation will outline an approach to (1) assess the current state, with its bottlenecks, gaps and pain points; (2) define a data centric future state, including the opportunities to implement data standards, like the AFO, ASM, ADF and others; and (3) create an actionable roadmap to deliver the changes and capabilities that power the execution of a data dependent strategy.
-
-
4:00pm - Group Discussion: What is your digital strategy? How can Allotrope technology help you realize it? (Moderated by Vinny Antonucci, Merck & Co, Inc)
-
Day 2 (April 26)
-
Allotrope Foundation and APN Members Only
-
Focus on strategic and implementation topics
-
Community project proposals and discussion
-
Opportunities for partnership with outside consortia
-
Expanding Allotrope into connecting domains (e.g., experimental modeling beyond results)
-
Lessons learned and questions raised from implementing Allotrope
-
Working group meetings
-
Day 3 (April 27)
-
Allotrope Foundation and APN Members Only
-
Board of Directors Meeting (Allotrope Board members only)
-
A Combined meeting of the technical Working Groups: in-person/remote hybrid session
-
Technical meetings and Product Team office hours
-